Name: O-DSMT | K2 Research Chemicals
SKU: o-dsmt
Price: 90.00 USD
Availability: InStock

O-Desmethyltramadol (O-DSMT) is an active metabolite of tramadol and a μ-opioid receptor agonist used in opioid pharmacology research.

Purity: ≥98% (HPLC)
Appearance: White crystalline powder
CAS: 73986-53-7
Molecular Formula: C15H23NO2
Molecular Weight: 249.35 g/mol
For research purposes only.

O-DSMT (O-Desmethyltramadol) is the primary active metabolite of tramadol and a potent

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-opioid receptor agonist synthesized strictly for analytical laboratory research, opioid pharmacology profiling, and comparative assays.

As a high-purity research chemical, O-DSMT (O-Desmethyltramadol) plays a critical role in studying opioid receptor binding dynamics, metabolic pathways, and structural activity relationships. Unlike its parent compound, it exhibits higher affinity for

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-opioid receptors while demonstrating reduced norepinephrine reuptake inhibition, making it an essential reference standard for mass spectrometry profiling and comparative analytical research. Every batch undergoes rigorous quality control testing to guarantee analytical purity, stability, and batch-to-batch consistency across laboratory procedures.

Chemical Specifications

Product Name: O-DSMT (O-Desmethyltramadol)
Chemical Name: 3-(2-(dimethylaminomethyl)-1-hydroxycyclohexyl)phenol hydrochloride
CAS Number: 73986-53-7 (hydrochloride) / 18559-59-6 (base)
Molecular Formula: C15H23NO2
Molecular Weight: 249.35 g/mol
Purity Standard: ≥98.0% (HPLC / GC-MS verified)
Physical Form: White to off-white crystalline powder
Storage Recommendation: Store sealed in a cool, dry place (-20°C recommended) protected from direct light, heat, and ambient moisture exposure.

Laboratory & Research Applications

This opioid reference standard is formulated for qualified scientific environments, including:

High-Performance Liquid Chromatography (HPLC) assay calibration and quantitative testing.
Gas Chromatography–Mass Spectrometry (GC-MS) qualitative identification.
In vitro opioid receptor binding affinity and receptor-ligand interaction assays.

Safety Notice: O-DSMT (O-Desmethyltramadol) is supplied strictly for authorized laboratory, analytical, and forensic research purposes only. This product is strictly not for human or veterinary consumption, in vivo diagnostic use, or therapeutic applications. Handle using standard personal protective equipment (PPE).