Phenyl-2-Nitropropene

Phenyl-2-Nitropropene (P2NP) crystalline. Chemical intermediate for research.

Product Name: P2NP (1-Phenyl-2-nitropropene) Synonyms: (2-Nitropropenyl)benzene; 2-nitro-1-phenylpropene; P2NP; phenyl-2-nitropropene

General Description: 1-Phenyl-2-nitropropene (P2NP) is formally described as a substituted nitroalkene. Unlike the psychoactive end-products previously listed, P2NP is not typically utilized as a drug of abuse itself. Instead, within forensic chemistry and law enforcement contexts, it is primarily recognized and heavily monitored as a direct chemical precursor used in the clandestine synthesis of amphetamine and heavily related substituted amphetamines.

In analytical and forensic toxicology, P2NP is utilized as a fundamental reference standard. It is essential for the calibration of analytical instrumentation (such as GC-MS, LC-MS/MS, and FTIR), the profiling of clandestine laboratory seizures, and the identification of synthetic impurities or unreacted intermediates in seized illicit street drugs. Route-specific impurity profiling of P2NP allows forensic chemists to determine the specific synthetic pathways employed by illicit manufacturers.

Technical Information:

• CAS Number: 705-60-2
• Molecular Formula: C₉H₉NO₂
• Formula Weight: 163.18 g/mol
• SMILES: CC(=CC1=CC=CC=C1)N+=O
• InChI Key: LFKXMFXIOFODMO-VOTSOKGWSA-N (Stereospecific, predominantly exists as the E-isomer)
• Formulation: Typically supplied as a bright yellow crystalline solid or as a certified reference material solution (e.g., 1 mg/mL in methanol or acetonitrile).

Biological Action: P2NP is a chemical intermediate and lacks the characteristic binding affinity for monoamine transporters or receptors seen in completed amphetamines; therefore, it does not produce classical psychostimulant or psychoactive effects. Toxicologically, nitroalkenes like P2NP are highly reactive electrophiles. Exposure poses significant health hazards, as the substance is a potent irritant to the eyes, skin, mucous membranes, and respiratory tract.

Regulatory and Safety Information:

• Intended Use: This product is intended strictly for use as an analytical reference standard for forensic, chemical profiling, and academic research purposes.
• Warning: This product is a highly reactive, irritating chemical precursor. It is completely devoid of recreational psychoactive properties and is highly toxic if ingested, inhaled, or absorbed through the skin. It is not for human or veterinary use.