PMK-Oil

PMK (Piperonyl methyl ketone) oil. Liquid chemical precursor for research.

Product Name: PMK-Oil (Piperonyl Methyl Ketone) Synonyms: 3,4-MDP2P; 3,4-Methylenedioxyphenyl-2-propanone; 1-(1,3-Benzodioxol-5-yl)propan-2-one; PMK

General Description: Piperonyl Methyl Ketone (PMK), frequently referred to colloquially and in law enforcement contexts as “PMK-Oil” due to its liquid state at room temperature, is formally described as 1-(1,3-benzodioxol-5-yl)propan-2-one. Unlike psychoactive end-products, PMK is not utilized as a drug of abuse itself. Instead, it is internationally recognized and heavily monitored as a primary chemical precursor utilized in the clandestine synthesis of MDMA (Ecstasy), MDA, MDEA, and other related methylenedioxyphenethylamines.

In analytical and forensic chemistry, pure PMK is utilized as a fundamental reference standard. It is essential for the calibration of analytical instrumentation (such as GC-MS, LC-MS/MS, and FTIR), the profiling of clandestine laboratory seizures, and the identification of synthetic impurities or unreacted intermediates in seized illicit street drugs. Route-specific impurity profiling of PMK allows forensic chemists to determine the specific synthetic pathways employed by illicit manufacturers and to track international precursor diversion.

Technical Information:

• CAS Number: 4676-39-5
• Molecular Formula: C₁₀H₁₀O₃
• Formula Weight: 178.19 g/mol
• SMILES: CC(=O)CC1=CC2=C(C=C1)OCO2
• InChI Key: WFFSECOENGWMCH-UHFFFAOYSA-N
• Formulation: Typically supplied as a neat, pale yellow to brownish viscous liquid (oil) or as a certified reference material solution (e.g., 1 mg/mL in methanol or acetonitrile) for analytical calibration.

Biological Action: PMK is a chemical intermediate and a substituted ketone; it lacks the characteristic binding affinity for monoamine transporters or receptors seen in completed entactogens or amphetamines. Therefore, it does not produce psychoactive or psychostimulant effects. Toxicologically, it is an industrial chemical and acts as a mild-to-moderate irritant to the eyes, skin, and respiratory tract upon exposure.

Regulatory and Safety Information:

• Intended Use: This product is intended strictly for use as an analytical reference standard for forensic, chemical profiling, and academic research purposes.
• Warning: This product is a highly restricted chemical precursor. It is completely devoid of recreational psychoactive properties and carries risks of chemical irritation if handled improperly. It is not for human or veterinary use.