3-MMC

3-MMC (3-Methylmethcathinone) is a synthetic cathinone derivative used in pharmacological research to study monoamine transporter interactions.

Purity: ≥98% (HPLC)
Appearance: White to off-white crystalline powder
Molecular Formula: C11H15NO
Molecular Weight: 177.24 g/mol
For research purposes only.

Product Name: 3-MMC (3-Methylmethcathinone) Synonyms: Metaphedrone; 3-Mephedrone; 3-Methyl-N-methylcathinone; 2-(methylamino)-1-(3-methylphenyl)propan-1-one

General Description: 3-MMC is formally described as 2-(methylamino)-1-(3-methylphenyl)propan-1-one. It is a synthetic, heavily psychoactive molecule belonging to the substituted cathinone class. Structurally, it is a positional isomer of the notorious designer drug 4-MMC (mephedrone), differing only in the placement of the methyl group on the phenyl ring (shifted from the para to the meta position). 3-MMC emerged prominently on the illicit designer drug market in the early 2010s as a novel psychoactive substance (NPS) specifically synthesized to circumvent global legislation banning mephedrone, rapidly gaining popularity for its potent entactogenic and stimulant properties.

In analytical, clinical, and forensic toxicology, 3-MMC is utilized as a fundamental reference standard. It is essential for the calibration of analytical instrumentation (such as LC-MS/MS, GC-MS, and HPLC) and the development of screening methodologies to identify and quantify the substance in seized materials, adulterated illicit street drugs, or biological matrices (e.g., whole blood, plasma, urine).

Technical Information (Hydrochloride Salt):

• CAS Number: 1246816-62-5 (Hydrochloride) / 1246815-51-9 (Freebase)
• Molecular Formula: C₁₁H₁₅NO • HCl
• Formula Weight: 213.70 g/mol (Hydrochloride) / 177.25 g/mol (Freebase)
• SMILES: CC1=CC(=CC=C1)C(=O)C(C)NC.Cl
• InChI Key: UIKWMNNUOGPEBD-UHFFFAOYSA-N (Freebase)
• Formulation: Typically supplied as a neat white-to-off-white crystalline solid or as a certified reference material solution (e.g., 1 mg/mL or 100 µg/mL in methanol).

Biological Action: Like its structural isomer mephedrone, 3-MMC acts as a potent monoamine releasing agent and reuptake inhibitor. It strongly interacts with the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT), forcefully increasing the extracellular concentrations of these neurotransmitters in the synaptic cleft. This combined dopaminergic and serotonergic activity mediates its intense euphoric, stimulatory, and empathogenic/entactogenic effects. Clinical presentations of acute 3-MMC intoxication include profound tachycardia, hypertension, hyperthermia, bruxism (jaw clenching), severe agitation, and a high risk of cardiovascular or neurological emergencies at supratherapeutic doses. Chronic abuse is associated with rapid tolerance and intense psychological dependence.

Regulatory and Safety Information:

• Intended Use: This product is intended strictly for use as an analytical reference standard for forensic, toxicological, and academic research purposes.